Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET (A) receptor antagonism

Endothelin-1 (ET-1) is a vasoconstrictor peptide which stimulates proliferation in vitro in different cell types, including colorectal cancer cells. Raised ET-1 levels have been detected both on tissue specimens and in the plasma of patients with cancers. To investigate the role of ET-1 in colorecta...

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Detalhes bibliográficos
Main Authors: Asham, E, Shankar, A, Loizidou, M, Fredericks, S, Miller, K, Boulos, P B, Burnstock, G, Taylor, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363991/
https://ncbi.nlm.nih.gov/pubmed/11742499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2193
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