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Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists

BACKGROUND—The vasoactive peptide endothelin 1 (ET-1) acts via two receptors, endothelin receptors A (ET(A)) and B (ET(B)). ET-1 is overexpressed by human cancers in vivo and in vitro and may be mitogenic for cancer cells.
METHOD—To elucidate if ET-1 is a growth regulator the following were investig...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ali, H, Loizidou, M, Dashwood, M, Savage, F, Sheard, C, Taylor, I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1728110/
https://ncbi.nlm.nih.gov/pubmed/11034585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.47.5.685
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