Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

Glycogen synthase kinase 3 (GSK-3) is implicated in multiple biological processes including metabolism, gene expression, cell fate determination, proliferation, and survival. GSK-3 activity is inhibited through phosphorylation of serine 21 in GSK-3α and serine 9 in GSK-3β. These serine residues of G...

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Main Authors: Fang, Xianjun, Yu, Shuang Xing, Lu, Yiling, Bast, Robert C., Woodgett, James R., Mills, Gordon B.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC17277/
https://ncbi.nlm.nih.gov/pubmed/11035810
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