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Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria.

The carbapenem imipenem and the penem CGP 31608 demonstrated unusually good bactericidal activity against slowly growing bacteria. In contrast to that of penicillin, the rate of killing was independent of growth rate. In logarithmically growing cells, a decrease in growth rate was paralleled by a de...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Cozens, R M, Markiewicz, Z, Tuomanen, E
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2574024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1819
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