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Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria.

The carbapenem imipenem and the penem CGP 31608 demonstrated unusually good bactericidal activity against slowly growing bacteria. In contrast to that of penicillin, the rate of killing was independent of growth rate. In logarithmically growing cells, a decrease in growth rate was paralleled by a de...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Cozens, R M, Markiewicz, Z, Tuomanen, E
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2574024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1819
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