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Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria.

The carbapenem imipenem and the penem CGP 31608 demonstrated unusually good bactericidal activity against slowly growing bacteria. In contrast to that of penicillin, the rate of killing was independent of growth rate. In logarithmically growing cells, a decrease in growth rate was paralleled by a de...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Cozens, R M, Markiewicz, Z, Tuomanen, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2574024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1819
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