Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus.

The in vitro inhibitory effects of quinolones on the bacterial DNA gyrase of Escherichia coli KL-16 and topoisomerase II of fetal calf thymus were compared. All the quinolones tested required higher concentrations to inhibit the topoisomerase II than to inhibit the DNA gyrase, and no correlation exi...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Hoshino, K, Sato, K, Une, T, Osada, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172762/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1816
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