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Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus.

The in vitro inhibitory effects of quinolones on the bacterial DNA gyrase of Escherichia coli KL-16 and topoisomerase II of fetal calf thymus were compared. All the quinolones tested required higher concentrations to inhibit the topoisomerase II than to inhibit the DNA gyrase, and no correlation exi...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Hoshino, K, Sato, K, Une, T, Osada, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1989
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1816
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