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pH and other effects on the antifungal activity of cilofungin (LY121019).

We investigated the effects of various test conditions on broth macro- and microdilution susceptibility test results for several species of yeasts with a new antifungal agent, cilofungin. As the pH decreased from 7.4 to 3.0, 50% inhibitory concentrations (IC1/2) increased up to 64-fold. This effect...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: McIntyre, K A, Galgiani, J N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172523/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2751286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.5.731
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