Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity

The neuropeptide galanin is expressed developmentally in the dorsal root ganglion (DRG) and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. Here we report that adult mice carrying a loss-of-function mutation in the galanin gene have a 13% reduction in the number of cell...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Holmes, Fiona E., Mahoney, Sally, King, Von R., Bacon, Andrea, Kerr, Niall C. H., Pachnis, Vassilis, Curtis, Rory, Priestley, John V., Wynick, David
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2000
Teme:	Biological Sciences
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11016970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.210221897
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