Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity

The neuropeptide galanin is expressed developmentally in the dorsal root ganglion (DRG) and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. Here we report that adult mice carrying a loss-of-function mutation in the galanin gene have a 13% reduction in the number of cell...

詳細記述

書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Holmes, Fiona E., Mahoney, Sally, King, Von R., Bacon, Andrea, Kerr, Niall C. H., Pachnis, Vassilis, Curtis, Rory, Priestley, John V., Wynick, David
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 2000
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11016970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.210221897
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