Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity
The neuropeptide galanin is expressed developmentally in the dorsal root ganglion (DRG) and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. Here we report that adult mice carrying a loss-of-function mutation in the galanin gene have a 13% reduction in the number of cell...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11016970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.210221897 |
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