Glucokinase-deficient mutant of Penicillium chrysogenum is derepressed in glucose catabolite regulation of both beta-galactosidase and penicillin biosynthesis.

One glucokinase-deficient mutant (glk1) of Penicillium chrysogenum AS-P-78 was isolated after germ tube-emitting spores were mutated with nitrosoguanidine and selected for growth on lactose-containing medium in the presence of inhibitory concentrations of D-2-deoxyglucose (3 mM). Penicillin biosynth...

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Yayımlandı:	Antimicrob Agents Chemother
Asıl Yazarlar:	Barredo, J L, Alvarez, E, Cantoral, J M, Diez, B, Martin, J F
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1988
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172344/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3142341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.32.7.1061
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