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The thioredoxin system of Penicillium chrysogenum and its possible role in penicillin biosynthesis.

Penicillium chrysogenum is an important producer of penicillin antibiotics. A key step in their biosynthesis is the oxidative cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to isopenicillin N by the enzyme isopenicillin N synthase (IPNS). bis-ACV, the oxidized disulfide form o...

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Publicat a:J Bacteriol
Autors principals: Cohen, G, Argaman, A, Schreiber, R, Mislovati, M, Aharonowitz, Y
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8106340/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.4.973-984.1994
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