Evolution of the recombination signal sequences in the Ig heavy-chain variable region locus of mammals
The Ig and T cell receptor (TCR) loci have an exceptionally dynamic evolutionary history, but the mechanisms responsible remain a subject of speculation. Ig and TCR genes are unique in vertebrates in that they are assembled from V, D, and J segments by site-specific recombination in developing lymph...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11415 |
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