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Werner protein recruits DNA polymerase δ to the nucleolus

Werner syndrome is a Mendelian disorder of man that produces a number of manifestations resembling human aging. This disorder is caused by inactivation of the wrn gene, a member of the RecQ family of DNA helicases. The helicase and exonuclease activities of the Werner protein (WRN) suggest that it f...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Szekely, Anna M., Chen, Yao-Hui, Zhang, Chunyu, Oshima, Junko, Weissman, Sherman M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17206/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11365
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