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Werner protein recruits DNA polymerase δ to the nucleolus

Werner syndrome is a Mendelian disorder of man that produces a number of manifestations resembling human aging. This disorder is caused by inactivation of the wrn gene, a member of the RecQ family of DNA helicases. The helicase and exonuclease activities of the Werner protein (WRN) suggest that it f...

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Autori principali: Szekely, Anna M., Chen, Yao-Hui, Zhang, Chunyu, Oshima, Junko, Weissman, Sherman M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17206/
https://ncbi.nlm.nih.gov/pubmed/11027336
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