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Distinct cAMP response element-binding protein (CREB) domains stimulate different steps in a concerted mechanism of transcription activation

Hormones and neurotransmitters rapidly change patterns of gene expression in target cells by activating protein kinases that phosphorylate and modify the activity of CREB and other transcription factors. Although CREB was initially characterized as mediating the response to cAMP, CREB phosphorylatio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kim, Jeong-a, Lu, Jingfang, Quinn, Patrick G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11292
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