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Distinct cAMP response element-binding protein (CREB) domains stimulate different steps in a concerted mechanism of transcription activation

Hormones and neurotransmitters rapidly change patterns of gene expression in target cells by activating protein kinases that phosphorylate and modify the activity of CREB and other transcription factors. Although CREB was initially characterized as mediating the response to cAMP, CREB phosphorylatio...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kim, Jeong-a, Lu, Jingfang, Quinn, Patrick G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17193/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11292
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