Distinct cAMP response element-binding protein (CREB) domains stimulate different steps in a concerted mechanism of transcription activation
Hormones and neurotransmitters rapidly change patterns of gene expression in target cells by activating protein kinases that phosphorylate and modify the activity of CREB and other transcription factors. Although CREB was initially characterized as mediating the response to cAMP, CREB phosphorylatio...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.21.11292 |
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