Effects of enoxacin on renal and metabolic clearance of theophylline in rats.
The effects of enoxacin and its metabolite 4-oxoenoxacin on the disposition of theophylline were investigated in rats. Systemic clearance of theophylline was significantly decreased by approximately 40, 46, and 50% after oral coadministration of 25, 100, and 200 mg of enoxacin per kg, respectively....
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2285287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.9.1739 |
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