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Effects of enoxacin on renal and metabolic clearance of theophylline in rats.

The effects of enoxacin and its metabolite 4-oxoenoxacin on the disposition of theophylline were investigated in rats. Systemic clearance of theophylline was significantly decreased by approximately 40, 46, and 50% after oral coadministration of 25, 100, and 200 mg of enoxacin per kg, respectively....

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Bibliografski detalji
Glavni autori: Nadai, M, Hasegawa, T, Kuzuya, T, Muraoka, I, Takagi, K, Yoshizumi, H
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC171915/
https://ncbi.nlm.nih.gov/pubmed/2285287
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