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Effects of enoxacin on renal and metabolic clearance of theophylline in rats.

The effects of enoxacin and its metabolite 4-oxoenoxacin on the disposition of theophylline were investigated in rats. Systemic clearance of theophylline was significantly decreased by approximately 40, 46, and 50% after oral coadministration of 25, 100, and 200 mg of enoxacin per kg, respectively....

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Nadai, M, Hasegawa, T, Kuzuya, T, Muraoka, I, Takagi, K, Yoshizumi, H
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1990
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2285287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.9.1739
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