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Treatment of murine coccidioidal meningitis with SCH39304.

The triazole SCH39304 was compared with itraconazole and fluconazole for treatment of murine coccidioidal meningitis. Mice were treated for 30 days with 1, 5, 10, or 30 mg of each drug per kg of body weight. Survival and brain tissue counts were measured. At equivalent doses, SCH39304 was more effec...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Defaveri, J, Sun, S H, Graybill, J R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2160794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.4.663
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