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Evidence for frequent gene conversion in the steroid 21-hydroxylase P-450(C21) gene: implications for steroid 21-hydroxylase deficiency.

Oligonucleotide probes specific for the deleterious mutations harbored in the P-450(C21)A pseudogene and oligonucleotide probes specific for the corresponding sequences in the B gene were prepared to examine the molecular lesions in the P-450(C21) gene of P-450(C21)-deficient patients. Using these g...

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Autors principals: Higashi, Y, Tanae, A, Inoue, H, Fujii-Kuriyama, Y
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715324/
https://ncbi.nlm.nih.gov/pubmed/2827462
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