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Pharmacokinetics of a novel quinolone, AT-4140, in animals.

The pharmacokinetics of 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(cis-3,5-dimethyl-1- piperazinyl)-4-oxoquinoline-3-carboxylic acid (AT-4140) in experimental animals given a single oral dose of 5 mg/kg were studied. The mean peak levels of AT-4140 in plasma of mice, rats, dogs, and monkeys w...

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Detalhes bibliográficos
Main Authors: Nakamura, S, Kurobe, N, Ohue, T, Hashimoto, M, Shimizu, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC171525/
https://ncbi.nlm.nih.gov/pubmed/2327763
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