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Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

Under pathologic conditions, renal tubular epithelial cells can undergo epithelial to mesenchymal transition (EMT), a phenotypic conversion that is believed to play a critical role in renal interstitial fibrogenesis. However, the underlying mechanism that governs this process remains largely unknown...

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Detalhes bibliográficos
Main Authors: Li, Yingjian, Yang, Junwei, Dai, Chunsun, Wu, Chuanyue, Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC171389/
https://ncbi.nlm.nih.gov/pubmed/12925691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317913
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