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Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors.

Von Hippel-Lindau (VHL) disease is a dominantly inherited disorder predisposing to retinal and CNS hemangioblastomas, renal cell carcinoma (RCC), pheochromocytoma, and pancreatic tumors. Interfamilial differences in predisposition to pheochromocytoma reflect allelic heterogeneity such that there is...

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Détails bibliographiques
Auteurs principaux: Prowse, A H, Webster, A R, Richards, F M, Richard, S, Olschwang, S, Resche, F, Affara, N A, Maher, E R
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1712486/
https://ncbi.nlm.nih.gov/pubmed/9106522
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