A high proportion of novel mutations in BRCA1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families

We have identified 79 mutations in BRCA1 in a set of 643 Dutch and 23 Belgian hereditary breast and ovarian cancer families collected either for research or for clinical diagnostic purposes. Twenty-eight distinct mutations have been observed, 18 of them not previously reported and 12 of them occurri...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Peelen, T., van Vliet, M., Petrij-Bosch, A., Mieremet, R., Szabo, C., van den Ouweland, A. M. W., Hogervorst, F., Brohet, R., Ligtenberg, M. J. L., Teugels, E., van der Luijt, R., van der Hout, A. H., Gille, J. J. P., Pals, G., Jedema, I., Olmer, R., van Leeuwen, I., Newman, B., Plandsoen, M., van der Est, M., Brink, G., Hageman, S., Arts, P. J. W., Bakker, M. M., Willems, H. W., van der Looij, E., Neyns, B., Bonduelle, M., Jansen, R., Oosterwijk, J. C., Sijmons, R., Smeets, H. J. M., van Asperen, C. J., Meijers-Heijboer, H., Klijn, J. G. M., de Greve, J., King, M.-C., Menko, F. H., Brunner, H. G., Halley, D., van Ommen, G.-J. B., Vasen, H. F. A., Cornelisse, C. J., van 'tVeer, L. J., de Knijff, P., Bakker, E., Devilee, P.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1712432/
https://ncbi.nlm.nih.gov/pubmed/9150151
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars