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High frequency of BRCA1/2 germline mutations in 42 Belgian families with a small number of symptomatic subjects

AIM—The initial risk assessments for BRCA1/2 mutation carriers and estimates of carrier frequencies were based on extended pedigrees with a large number of symptomatic subjects. When counselling based on BRCA gene mutation analysis was initiated, we faced requests for counselling mostly from members...

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Détails bibliographiques
Auteurs principaux: Goelen, G, Teugels, E, Bonduelle, M, Neyns, B, De Greve, J
Format: Artigo
Langue:Inglês
Publié: BMJ Group 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734354/
https://ncbi.nlm.nih.gov/pubmed/10227398
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