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De novo recurrent germline mutation of the BRCA2 gene in a patient with early onset breast cancer

Germline mutations in either of the two major breast cancer predisposition genes, BRCA1 and BRCA2, account for a significant proportion of hereditary breast/ovarian cancer. Identification of breast cancer patients carrying mutations of these genes is primarily based on a positive family history of b...

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Autors principals: van der Luijt, R. B, van Zon, P. H A, Jansen, R., van der Sijs-Bos, C. J M, Warlam-Rodenhuis, C., Ausems, M.
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1734809/
https://ncbi.nlm.nih.gov/pubmed/11158174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.38.2.102
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