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A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma

BACKGROUND: Several studies showed that gain-of-function somatic mutations affecting the catalytic domain of EGFR in non-small cell lung carcinomas were associated with response to gefitinib and erlotinib, both EGFR-tyrosine kinase inhibitors. In addition, 4% of non-small cell lung carcinomas were s...

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Detalhes bibliográficos
Main Authors: Bekaii-Saab, Tanios, Williams, Nita, Plass, Christoph, Calero, Miguel Villalona, Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1712353/
https://ncbi.nlm.nih.gov/pubmed/17150109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-278
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