A Ras activation pathway dependent on Syk phosphorylation of protein kinase C

Protein kinase C (PKC) and Syk protein tyrosine kinase play critical roles in immune cell activation including that through the high-affinity IgE receptor, FcεRI. Mechanisms by which PKC activation leads to the activation of Ras, a family of GTPases essential for immune cell activation, have been el...

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Bibliographische Detailangaben
Hauptverfasser: Kawakami, Yuko, Kitaura, Jiro, Yao, Libo, McHenry, Robert W., Kawakami, Yu, Newton, Alexandra C., Kang, Shin, Kato, Roberta M., Leitges, Michael, Rawlings, David J., Kawakami, Toshiaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC170942/
https://ncbi.nlm.nih.gov/pubmed/12881490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633695100
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