Standardization of an opsonophagocytic assay for the measurement of functional antibody activity against Streptococcus pneumoniae using differentiated HL-60 cells.

Host protection against pneumococcal disease i primarily mediated by phagocytosis. We developed and standardized an opsonophagocytic assay using HL-60 cells (human promyelocytic leukemia cells). Fifty-five serum samples were analyzed for the presence of functional antibody against seven pneumococcal...

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Bibliographic Details
Main Authors: Romero-Steiner, S, Libutti, D, Pais, L B, Dykes, J, Anderson, P, Whitin, J C, Keyserling, H L, Carlone, G M
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC170543/
https://ncbi.nlm.nih.gov/pubmed/9220157
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