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Sequence-dependent gating of an ion channel by DNA hairpin molecules

DNA hairpins produce ionic current signatures when captured by the alpha-hemolysin nano-scale pore under conditions of single molecule electrophoresis. Gating patterns produced by individual DNA hairpins when captured can be used to distinguish differences of a single base pair or even a single nucl...

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Bibliografiske detaljer
Main Authors: DeGuzman, Veronica S., Lee, Clarence C., Deamer, David W., Vercoutere, Wenonah A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702491/
https://ncbi.nlm.nih.gov/pubmed/17130164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl754
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