Discrimination among individual Watson–Crick base pairs at the termini of single DNA hairpin molecules

Nanoscale α-hemolysin pores can be used to analyze individual DNA or RNA molecules. Serial examination of hundreds to thousands of molecules per minute is possible using ionic current impedance as the measured property. In a recent report, we showed that a nanopore device coupled with machine learni...

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Main Authors: Vercoutere, Wenonah A., Winters-Hilt, Stephen, DeGuzman, Veronica S., Deamer, David, Ridino, Sam E., Rodgers, Joseph T., Olsen, Hugh E., Marziali, Andre, Akeson, Mark
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC150236/
https://ncbi.nlm.nih.gov/pubmed/12582251
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