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Synthesis with Good Enantiomeric Excess of Both Enantiomers of α-Ketols and Acetolactates by Two Thiamin Diphosphate Dependent Decarboxylases.

In addition to the decarboxylation of 2-oxo acids, thiamin diphosphate (ThDP)-dependent decarboxylases/dehydrogenases can also carry out so-called carboligation reactions, where the central ThDP-bound enamine intermediate reacts with electrophilic substrates. For example, the enzyme yeast pyruvate d...

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Bibliografiske detaljer
Main Authors: Baykal, Ahmet, Chakraborty, Sumit, Dodoo, Afua, Jordan, Frank
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702321/
https://ncbi.nlm.nih.gov/pubmed/17083961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2006.09.006
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