Detection of methylation of human p16(Ink4a) gene 5′-CpG islands by electrochemical method coupled with linker-PCR

Aberrant DNA methylation of the CpG site is among the earliest and most frequent alterations in cancer. Detection of promoter hypermethylation of cancer-related genes may be useful for cancer diagnosis or the detection of recurrence. p16, an inhibitor of the cyclin D-dependent protein kinases, is a...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Hou, Peng, Ji, Meiju, Ge, Cunwang, Shen, Jiayao, Li, Song, He, Nongyue, Lu, Zuhong
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2003
Soggetti:	NAR Methods Online
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169984/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng092
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