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A yeast knockout strain to discriminate between active and inactive tRNA molecules

Here we report the construction of a yeast genetic screen designed to identify essential residues in tRNA(Arg). The system consists of a tRNA(Arg) knockout strain and a set of vectors designed to rescue and select for variants of tRNA(Arg). By plasmid shuffling we selected inactive tRNA mutants that...

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Bibliografiske detaljer
Main Authors: Geslain, Renaud, Martin, Franck, Camasses, Alain, Eriani, Gilbert
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC169964/
https://ncbi.nlm.nih.gov/pubmed/12907713
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