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Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase

The role of cysteine sulfhydryl residues on the RNA binding activity of human thymidylate synthase (TS) was investigated by mutating each cysteine residue on human TS to a corresponding alanine residue. Enzymatic activities of TS:C43A and TS:C210A mutant proteins were nearly identical to wild-type T...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphov: Lin, Xiukun, Liu, Jun, Maley, Frank, Chu, Edward
Materialtyp: Artigo
Språk:Inglês
Utgiven: Oxford University Press 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg678
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