Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase

The role of cysteine sulfhydryl residues on the RNA binding activity of human thymidylate synthase (TS) was investigated by mutating each cysteine residue on human TS to a corresponding alanine residue. Enzymatic activities of TS:C43A and TS:C210A mutant proteins were nearly identical to wild-type T...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Lin, Xiukun, Liu, Jun, Maley, Frank, Chu, Edward
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169953/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg678
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