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In vitro selection of an RNA sequence that interacts with high affinity with thymidylate synthase

Previous studies have shown that the repressive effect of thymidylate synthase (TS) mRNA translation is mediated by direct binding of TS itself to two cis-acting elements on its cognate mRNA. To identify the optimal RNA nucleotides that interact with TS, we in vitro synthesized a completely degenera...

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Bibliografiska uppgifter
Huvudupphovsmän: Lin, Xiukun, Mizunuma, Nobuyuki, Chen, Tian-men, Copur, Sitki M., Maley, Gladys F., Liu, Jun, Maley, Frank, Chu, Edward
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC113123/
https://ncbi.nlm.nih.gov/pubmed/11058126
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