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Hydropathic analysis of the free energy differences in anthracycline antibiotic binding to DNA

Molecular models of six anthracycline antibiotics and their complexes with 32 distinct DNA octamer sequences were created and analyzed using HINT (Hydropathic INTeractions) to describe binding. The averaged binding scores were then used to calculate the free energies of binding for comparison with e...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Nucleic Acids Res
Үндсэн зохиолчид: Cashman, Derek J., Scarsdale, J. Neel, Kellogg, Glen E.
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Oxford University Press 2003
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169931/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12888500/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg645
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