Hydropathic analysis of the free energy differences in anthracycline antibiotic binding to DNA

Molecular models of six anthracycline antibiotics and their complexes with 32 distinct DNA octamer sequences were created and analyzed using HINT (Hydropathic INTeractions) to describe binding. The averaged binding scores were then used to calculate the free energies of binding for comparison with e...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Cashman, Derek J., Scarsdale, J. Neel, Kellogg, Glen E.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 2003
Pynciau:	Articles
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12888500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg645
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