Hydropathic analysis of the free energy differences in anthracycline antibiotic binding to DNA

Molecular models of six anthracycline antibiotics and their complexes with 32 distinct DNA octamer sequences were created and analyzed using HINT (Hydropathic INTeractions) to describe binding. The averaged binding scores were then used to calculate the free energies of binding for comparison with e...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Autores principales:	Cashman, Derek J., Scarsdale, J. Neel, Kellogg, Glen E.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 2003
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12888500/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg645
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