Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA

The chicken anaemia virus-derived protein apoptin is a tumour-specific cell-killing agent. It is biologically active as a highly stable, multimeric complex, consisting of 30–40 monomers. In tumour cells, but negligibly in normal cells, apoptin is imported into the nucleus prior to the induction of a...

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Huvudupphovsmän: Leliveld, Sirik R., Dame, Remus T., Mommaas, Mieke A., Koerten, Henk K., Wyman, Claire, Danen-van Oorschot, Astrid A. A. M., Rohn, Jennifer L., Noteborn, Mathieu H. M., Abrahams, Jan Pieter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC169900/
https://ncbi.nlm.nih.gov/pubmed/12907722
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