Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA
The chicken anaemia virus-derived protein apoptin is a tumour-specific cell-killing agent. It is biologically active as a highly stable, multimeric complex, consisting of 30–40 monomers. In tumour cells, but negligibly in normal cells, apoptin is imported into the nucleus prior to the induction of a...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12907722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg661 |
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