Activation of the Tumor-Specific Death Effector Apoptin and Its Kinase by an N-Terminal Determinant of Simian Virus 40 Large T Antigen

Apoptin, a viral death protein derived from chicken anemia virus, displays a number of tumor-specific behaviors. In particular, apoptin is phosphorylated, translocates to the nucleus, and induces apoptosis specifically in tumor or transformed cells, whereas it is nonphosphorylated and remains primar...

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Hlavní autoři: Zhang, Ying-Hui, Kooistra, Klaas, Pietersen, Alexandra, Rohn, Jennifer L., Noteborn, Mathieu H. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC515021/
https://ncbi.nlm.nih.gov/pubmed/15331730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.18.9965-9976.2004
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