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Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA
The chicken anaemia virus-derived protein apoptin is a tumour-specific cell-killing agent. It is biologically active as a highly stable, multimeric complex, consisting of 30–40 monomers. In tumour cells, but negligibly in normal cells, apoptin is imported into the nucleus prior to the induction of a...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Oxford University Press
2003
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169900/ https://ncbi.nlm.nih.gov/pubmed/12907722 |
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