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p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration

Internalization and proteolytic degradation of epidermal growth factor (EGF) receptor (R) following ligand binding is an important mechanism for regulating EGF-stimulated signals. Using pharmacological and RNA interference inhibition of p38 mitogen-activated protein kinase, we show that p38 is requi...

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Detaylı Bibliyografya
Asıl Yazarlar: Frey, Mark R, Dise, Rebecca S, Edelblum, Karen L, Polk, D Brent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698902/
https://ncbi.nlm.nih.gov/pubmed/17139251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601457
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