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The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels
TRPV4 is a widely expressed member of the transient receptor potential (TRP) family that facilitates Ca(2+) entry into nonexcitable cells. TRPV4 is activated by several stimuli, but it is largely unknown how the activity of this channel is terminated. Here, we show that ubiquitination represents an...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698878/ https://ncbi.nlm.nih.gov/pubmed/17110928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601429 |
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